LY2389575

Ligand id: 9694

Name: LY2389575

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 41.05
Molecular weight 399.99
XLogP 4.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3S)-1-(5-bromopyrimidin-2-yl)-N-[(2,4-dichlorophenyl)methyl]pyrrolidin-3-amine
Synonyms
LY 2389575 | LY-2389575
Comments
LY2389575 is a negative allosteric modulator (NAM) that is selective for the metabotropic glutamate receptor 3 [1]. May be used experimentally as the hydrochloride salt.
Database Links
ChEMBL Ligand CHEMBL2204436
GtoPdb PubChem SID 348353653
PubChem CID 11503055
Search Google for chemical match using the InChIKey PXQNLQLMRMROSB-ZDUSSCGKSA-N
Search Google for chemicals with the same backbone PXQNLQLMRMROSB
Search UniChem for chemical match using the InChIKey PXQNLQLMRMROSB-ZDUSSCGKSA-N
Search UniChem for chemicals with the same backbone PXQNLQLMRMROSB