isunakinra   Click here for help

GtoPdb Ligand ID: 9704

Synonyms: EBI-005
Immunopharmacology Ligand
Compound class: Peptide
Comment: Isunakinra (EBI-005) is a fusion protein containing domains from IL-1β and IL-1 receptor antagonist (IL-1Ra or anakinra) [3]. It potently blocks IL-1R1 signalling, with higher affinity than anakinra. It was developed as a topical therapy for inflammatory diseases of the ocular surface.
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Classification Click here for help
Compound class Peptide
International Nonproprietary Names Click here for help
INN number INN
10091 isunakinra
Synonyms Click here for help
EBI-005
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9681764
Reactome Reaction Reactome logo R-HSA-9681763
Other databases
ChEMBL Ligand CHEMBL3545190
DrugBank Ligand DB12373
GtoPdb PubChem SID 348353663
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