fosmidomycin

Ligand id: 9739

Name: fosmidomycin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 107.88
Molecular weight 183.03
XLogP -2.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Ligand families/groups Antimalarial ligands
IUPAC Name
3-(formyl-hydroxyamino)propylphosphonic acid
International Nonproprietary Names
INN number INN
5104 fosmidomycin
Synonyms
FR-31564
Comments
Fosmidomycin was first identified as antibiotic but also has antimalarial activity.

The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Database Links
CAS Registry No. 66508-53-0 (source: Scifinder)
ChEBI CHEBI:443725
ChEMBL Ligand CHEMBL203125
DrugBank Ligand DB02948
GtoPdb PubChem SID 374883827
PubChem CID 572
RCSB PDB Ligand FOM
Search Google for chemical match using the InChIKey GJXWDTUCERCKIX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GJXWDTUCERCKIX
Search PubMed clinical trials fosmidomycin
Search PubMed titles fosmidomycin
Search PubMed titles/abstracts fosmidomycin
Search UniChem for chemical match using the InChIKey GJXWDTUCERCKIX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GJXWDTUCERCKIX
Wikipedia Fosmidomycin