tepilamide fumarate

Ligand id: 9770

Name: tepilamide fumarate

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 72.91
Molecular weight 243.11
XLogP 0.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Is prodrug? Yes
Active form monomethyl fumarate
IUPAC Name
4-O-[2-(diethylamino)-2-oxoethyl] 1-O-methyl (E)-but-2-enedioate
International Nonproprietary Names
INN number INN
10672 tepilamide fumarate
Synonyms
XP 23829 | XP-23829 | XP23829
Comments
Tepilamide fumarate (XP23829) is a small-molecule fumaric acid ester prodrug of monomethyl fumarate (MMF). It is being developed by Arbor Pharmaceuticals (formerly XenoPort) as a potential treatment for autoinflammatory diseases.
Database Links
GtoPdb PubChem SID 354702243
PubChem CID 46179632
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