Synonyms: β-arteether
Compound class:
Synthetic organic
Comment: Artemotil is a semisynthetic derivative of artemisinin, a natural product isolated from the qinghao or sweet wormwood plant (Artemisia annua). It contains an unusual endoperoxide bridge, believed to be responsible for the antimalarial activity of artemisinin and its derivatives.
Artemotil is a prodrug that is converted to the active metabolite artenimol (dihydroartemisinin). The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
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Classification ![]() |
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Compound class | Synthetic organic |
Ligand families/groups | Antimalarial ligands |
IUPAC Name ![]() |
(1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
International Nonproprietary Names ![]() |
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INN number | INN |
6457 | artemotil |
Synonyms ![]() |
β-arteether |
Database Links ![]() |
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CAS Registry No. | 75887-54-6 (source: Scifinder) |
ChEBI | CHEBI:135335 |
ChEMBL Ligand | CHEMBL301267 |
DrugCentral Ligand | 246 |
GtoPdb PubChem SID | 374883845 |
PubChem CID | 3000469 |
Search Google for chemical match using the InChIKey | NLYNIRQVMRLPIQ-XQLAAWPRSA-N |
Search Google for chemicals with the same backbone | NLYNIRQVMRLPIQ |
Search PubMed clinical trials | artemotil |
Search PubMed titles | artemotil |
Search PubMed titles/abstracts | artemotil |
UniChem Compound Search for chemical match using the InChIKey | NLYNIRQVMRLPIQ-XQLAAWPRSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NLYNIRQVMRLPIQ-XQLAAWPRSA-N |
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Artemotil (links to external site)
Cat. No. HY-B0770 |