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Compound class: Synthetic organic
Comment: Ferroquine is a 4-aminoquinoline antimalarial compound with a novel ferrocenic group in its side chain.
The ferrocenic group causes rendering problems, with different images of the chemical structure found across web resources. We show the structure provided by NIH US National Library of Medicine (InChIKey IRJOHJGUSPNBRI-UHFFFAOYSA-N). PubChem provide a different InChIKey DLYPREQTTOHKSM-UHFFFAOYSA-N with two structural representations PubChem CID 56841801 (link in table below) and PubChem CID 76419023.
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|Ligand families/groups||Antimalarial ligands|
|International Nonproprietary Names|
|CAS Registry No.||185055-67-8 (source: Scifinder)|
|GtoPdb PubChem SID||374883859|
|Search Google for chemical match using the InChIKey||IRJOHJGUSPNBRI-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||IRJOHJGUSPNBRI|
|Search PubMed clinical trials||ferroquine|
|Search PubMed titles||ferroquine|
|Search PubMed titles/abstracts||ferroquine|
|Search UniChem for chemical match using the InChIKey||IRJOHJGUSPNBRI-UHFFFAOYSA-N|
|Search UniChem for chemicals with the same backbone||IRJOHJGUSPNBRI|