sarafotoxin S6c   Click here for help

GtoPdb Ligand ID: 1008

Synonyms: S6C | Sarafotoxin-C | SRTX-C
Comment: From Atractaspis engaddensis (Israeli burrowing asp). Representations of the chemical structure of sarafotoxin S6c can be found in the links above.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
ETB receptor Rn Agonist Full agonist 10.2 – 10.8 pKd - 2-3
pKd 10.2 – 10.8 [2-3]
ETB receptor Hs Agonist Full agonist 8.8 – 9.8 pKd - 1-2
pKd 8.8 – 9.8 (Kd 1.6x10-9 – 1.6x10-10 M) [1-2]