NUDT7-COV-1

Ligand id: 10384

Name: NUDT7-COV-1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 49.41
Molecular weight 390.09
XLogP 3.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
nudix hydrolase 7 Hs Inhibitor Inhibition 6.0 pIC50 - 1
pIC50 6.0 (IC50 1.1x10-6 M) [1]
Description: In an enzymatic assay monitoring NUDT7-induced acetyl-CoA hydrolysis; 30 minutes pre-incubation with inhibitor.