enfortumab vedotin   Click here for help

GtoPdb Ligand ID: 10738

Synonyms: ASG-22CE | enfortumab vedotin-ejfv | Padcev®
Approved drug
enfortumab vedotin is an approved drug (FDA (2019), EMA (2022))
Compound class: Antibody
Comment: Enfortumab vedotin is an anti-Nectin 4 monoclonal antibody-drug conjugate [3]. The toxic payload is monomethyl auristatin E (MMAE; PubChem CID 11542188). It exhibits potent efficacy in multiple preclinical cancer models [1].
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
nectin cell adhesion molecule 4 Primary target of this compound Hs Antibody Binding - - - 3
⤷ [3]