Synonyms: analogue 4f [Brown et al., 1991] [1] | BRL44154
Compound class:
Synthetic organic
Comment: Strictly this is the parent molecule of BRL-44154 which referes to the sodium salt. BRL-44154 is a penicillin class antibacterial that was developed by SmithKline Beecham [2]. It has high stability to β-lactamases.
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Bioactivity Comments |
The MIC for antibacterial activity against β-lactamase-producing H. infiuenzae NEMC1 is 0.25 μg/ml in vitro, the MIC against methicillin-resistant S. aureus V573 is 2 μg/ml [1]. |