Synonyms: LY-3039478 | LY3039478
Compound class:
Synthetic organic
|
|
Bioactivity Comments |
Crenigacestat inhibits γ-secretase-madiated cleavage of NOTCH1 in MDA-MB-231 cancer cells with an IC50 of 0.5 nM [1]. Since γ-secretase is a protein complex we are unable to allocate the inhibitory action of crenigacestat to a single protein. |