Ugr 9-1   Click here for help

GtoPdb Ligand ID: 11475

Synonyms: π-AnmTX Ugr 9a-1
Comment: Ugr 9-1 is a derivative of a sea anemone peptide toxin from Urticina grebelnyi. it acts as a reversible inhibitor of ASIC3 ion channels [1].
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
ASIC3 Hs Channel blocker - 5.0 pIC50 - 1
pIC50 5.0 (IC50 1x10-5 M) transient component [1]