Synonyms: analog 35b [PMID: 20163176] | MK-7009 | MK7009 | Vanihep®
vaniprevir is an approved drug (Japan 2014)
Compound class:
Synthetic organic
|
|
Bioactivity Comments |
Vaniprevir (MK-7009) inhibits genotype 1 and genotype 2 NS3/4a protease enzymes [3]. The Ki for inhibition of genotype 1b NS3/4a protease is 0.05 nM, and for genotype 2a NS3/4a protease it is 0.9 nM. |