Ligand id: 1425

Name: [3H]M-MPEP    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 22.12
Molecular weight 223.1
XLogP 3.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
mGlu5 receptor Hs Allosteric modulator Negative 8.3 – 8.4 pIC50 - 1-2
pIC50 8.4 [1]
pIC50 8.3 [2]
Ligand mentioned in the following text fields