PHV

Ligand id: 2275

Name: PHV

Species: Rat

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
PAC1 receptor
VPAC1 receptor
VPAC2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
VPAC1 receptor Rn Agonist Agonist 8.5 pIC50 - 1
pIC50 8.5 (IC50 3x10-9 M) [1]
Description: inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor
VPAC2 receptor Rn Agonist Agonist 8.2 pIC50 - 1
pIC50 8.2 (IC50 6x10-9 M) [1]
Description: inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor
VPAC2 receptor Hs Agonist Agonist 8.0 pIC50 - 1
pIC50 8.0 (IC50 1x10-8 M) [1]
Description: inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor
VPAC1 receptor Hs Agonist Agonist 5.5 pIC50 - 1
pIC50 5.5 (IC50 3x10-6 M) [1]
Description: inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor