R-spondin-3   Click here for help

GtoPdb Ligand ID: 3699

Synonyms: hPWTSR | hRspo3 | Roof plate-specific spondin-3
Species: Human
Click here for help
Natural/Endogenous Targets
Target
LGR4
LGR5
LGR6
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
LGR4 Hs Agonist Full agonist 8.7 pKd - 3
pKd 8.7 (Kd 2.2x10-9 M) [3]
LGR5 Ligand is endogenous in the given species Hs Agonist Full agonist 11.0 pEC50 - 1
pEC50 11.0 (EC50 1x10-11 M) [1]
LGR4 Ligand is endogenous in the given species Hs Agonist Full agonist 10.7 pEC50 - 1
pEC50 10.7 (EC50 2x10-11 M) [1]
LGR6 Ligand is endogenous in the given species Hs Agonist Agonist - - - 1-2
[1-2]