sclerostin   Click here for help

GtoPdb Ligand ID: 3704

Abbreviated name: SOST
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Other ligands which bind to or alter the activity of this ligand
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Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
romosozumab Peptide Approved drug Primary target of this compound Hs Antibody Binding 11.2 – 12.2 pKd - 1
⤷ pKd 11.2 – 12.2 (Kd 6x10-12 – 6x10-13 M) [1]
Description: Affinity across a range of antibodies tested, as the lead antibody is not indicated in the patent.
BPS-804 Peptide Primary target of this compound Hs Antibody Binding - - -
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Ligand mentioned in the following text fields
Class Frizzled GPCRs overview
Class Frizzled GPCRs comments