IL-17B   Click here for help

GtoPdb Ligand ID: 5877

Immunopharmacology Ligand
Comment: IL-17B is a proinflammatory homolog of IL-17 expressed at very high levels in spinal cord (primarily localizing to neuronal cell bodies and axons) and at lower levels in trachea, prostate, lung, small intestine, testes, adrenal, and pancreas [2-3], and acting on a restricted set of target cells (IL-17B receptor expression is restricted to human kidney, pancreas, liver, brain, and intestines [3]).
Species: Human
Natural/Endogenous Targets
Target
Interleukin-25 receptor
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-25 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -