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Abbreviated name: VN
Synonyms: S-protein | serum-spreading factor | V75
Compound class:
Endogenous peptide in human, mouse or rat
Comment: The vitronectin precursor protein can be cleaved into three subunits: vitronectin V65 subunit, vitronectin V10 subunit and somatomedin-B. Vitronectin can exist in two forms, one being a single chain uncleaved form (V75), and the other a cleaved form composed of the V65 and V10 subunits which are held together by a disulfide bond.
Species: Human
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| Additional information and targets (data relate to human unless otherwise stated) | ||
| Description | Data | Reference |
| Ligands at integrin αIIbβ3 | fibrinogen (FGA, FGB, FGG, P02671, P02675, P02679), fibronectin (FN1, P02751), von Willebrand factor (VWF, P04275), vitronectin (VTN, P04004), thrombospondin | |
| Ligands at integrin αVβ3 | vitronectin (VTN, P04004), fibronectin (FN1, P02751), fibrinogen (FGA, FGB, FGG, P02671, P02675, P02679), osteopontin (SPP1, P10451), von Willebrand factor (VWF, P04275), thrombospondin, tenascin | |
| Ligand mentioned in the following text fields |
| Integrins comments |
