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Synonyms: Voraxaze®
glucarpidase is an approved drug (FDA (2012), EMA (2022))
Compound class:
Peptide or derivative
Comment: Glucarpidase, a recombinant form of the bacterial enzyme carboxypeptidase G2 (cpg2). Pseudomonas sp cpg2 has UniProt id P06621.
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| Bioactivity Comments |
| As this drug metabolises an exogenously introduced compound (methotrexate) it does not act at a classic human primary target. |
