Synonyms: AT-4140 | AT4140 | CI-978 | CI978 | SPFX | Zagam ®
sparfloxacin is an approved drug (FDA (1996))
Compound class:
Synthetic organic
Comment: Sparfloxacin is a fluoroquinolone antibacterial. It has a less than ideal side-effect profile [3] that led to its withdrawl from the US market.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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No information available. |
Summary of Clinical Use |
Sparfloxacin was approved to treat bronchitis and bacterial pneumonia, but was withdrawn from the US market due to toxicity issues, including phototoxicity. |
External links |
For extended ADME data see the following: Drugs.com |