Synonyms: WCK 4873 | WCK-4873 | WCK4873
Compound class:
Synthetic organic
Comment: Nafithromycin (WCK-4873) is a ketolide antibacterial with Gram-positive activity [1-2].
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References |
1. Flamm RK, Rhomberg PR, Sader HS. (2017)
In Vitro Activity of the Novel Lactone Ketolide Nafithromycin (WCK 4873) against Contemporary Clinical Bacteria from a Global Surveillance Program. Antimicrob Agents Chemother, 61 (12). [PMID:28971877] |
2. Hackel MA, Karlowsky JA, Dressel D, Sahm DF. (2017)
Determination of Disk Diffusion and MIC Quality Control Ranges for Nafithromycin (WCK 4873), a New Lactone-Ketolide. J Clin Microbiol, 55 (10): 3021-3027. [PMID:28747372] |
3. Iwanowski P, Bhatia A, Gupta M, Patel A, Chavan R, Yeole R, Friedland D. (2019)
Safety, tolerability and pharmacokinetics of oral nafithromycin (WCK4873) after single or multiple doses and effects of food on single-dose bioavailability in healthy adult subjects. Antimicrob Agents Chemother, 63 (12). [PMID:31591119] |