Synonyms: Dificid® | Dificlir® | lipiarmycin | OPT-80 | PAR-101 | tiacumicin B
fidaxomicin is an approved drug (EMA & FDA (2011))
Compound class:
Synthetic organic
Comment: Fidaxomicin is a narrow-spectrum, semisynthetic, macrolide antibacterial. It was isolated from the hamdenensis subspecies of actinomycete Dactylosporangium aurantiacum.
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References |
1. Chen C, Doll NK, Casadei G, Bremner JB, Lewis K, Kelso MJ. (2014)
Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells. Bioorg Med Chem Lett, 24 (2): 595-600. [PMID:24360560] |
2. Karlowsky JA, Laing NM, Zhanel GG. (2008)
In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile. Antimicrob Agents Chemother, 52 (11): 4163-5. [PMID:18725442] |