Synonyms: ABT-493 | ABT493 | Maviret® | Mavyret® (glecaprevir + pibrentasvir)
glecaprevir is an approved drug (EMA & FDA (2017))
Compound class:
Synthetic organic
Comment: Glecaprevir is an orally available anti-hepatitis C virus (HCV) drug. It is a direct-acting inhibitor of the HCV NS3/4A protease, and thereby targets viral RNA replication.
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References |
1. Lawitz EJ, O'Riordan WD, Asatryan A, Freilich BL, Box TD, Overcash JS, Lovell S, Ng TI, Liu W, Campbell A et al.. (2015)
Potent Antiviral Activities of the Direct-Acting Antivirals ABT-493 and ABT-530 with Three-Day Monotherapy for Hepatitis C Virus Genotype 1 Infection. Antimicrob Agents Chemother, 60 (3): 1546-55. [PMID:26711747] |