[3H]M-MPEP

Ligand id: 1425

Name: [3H]M-MPEP    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 22.12
Molecular weight 223.1
XLogP 3.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Gasparini F, Andres H, Flor PJ, Heinrich M, Inderbitzin W, Lingenhohl K, Muller H, Munk VC, Omilusik K, Stierlin C, Stoehr N, Vranesic I, Kuhn R. (2002)
[(3)H]-M-MPEP, a potent, subtype-selective radioligand for the metabotropic glutamate receptor subtype 5.
Bioorg Med Chem Lett., 12: 407-409. [PMID:11814808]
2. O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL Jr. (2003)
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
Mol Pharmacol., 64: 731-740. [PMID:12920211]