compound 1f [PMID: 2153213]

Ligand id: 2990

Name: compound 1f [PMID: 2153213]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 82.17
Molecular weight 437.2
XLogP 4.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Jendralla H, Baader E, Bartmann W, Beck G, Bergmann A, Granzer E, von Kerekjarto B, Kesseler K, Krause R, Schubert W. (1990)
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 2. Derivatives of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) acids.
J. Med. Chem., 33 (1): 61-70. [PMID:2153213]