Synonyms: [3H]PZ
Compound class:
Synthetic organic
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
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The Impact of Removal of Ovarian Hormones on Cholinergic Muscarinic Receptors: Examining Prepulse Inhibition and Receptor Binding. Brain Sci, 10 (2). [PMID:32079174] |
2. Eveleigh P, Hulme EC, Schudt C, Birdsall NJ. (1989)
The existence of stable enantiomers of telenzepine and their stereoselective interaction with muscarinic receptor subtypes. Mol Pharmacol, 35 (4): 477-83. [PMID:2704371] |
3. Hammer R, Berrie CP, Birdsall NJ, Burgen AS, Hulme EC. (1980)
Pirenzepine distinguishes between different subclasses of muscarinic receptors. Nature, 283 (5742): 90-2. [PMID:7350532] |
4. Scarr E, Dean B. (2008)
Muscarinic receptors: do they have a role in the pathology and treatment of schizophrenia?. J Neurochem, 107 (5): 1188-95. [PMID:18957051] |
5. Valuskova P, Farar V, Forczek S, Krizova I, Myslivecek J. (2018)
Autoradiography of 3H-pirenzepine and 3H-AFDX-384 in Mouse Brain Regions: Possible Insights into M1, M2, and M4 Muscarinic Receptors Distribution. Front Pharmacol, 9: 124. [PMID:29515448] |
6. Watson M, Roeske WR, Johnson PC, Yamamura HI. (1984)
[3H]Pirenzepine identifies putative M1 muscarinic receptors in human stellate ganglia. Brain Res, 290 (1): 179-82. [PMID:6546354] |