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Synonyms: Vonvendi® | vWF
von Willebrand factor is an approved drug (FDA (2015))
Compound class:
Endogenous peptide in human, mouse or rat
Comment: Details of the structure of von Willebrand factor (vWF) are available in its UniProt record. The pre-pro peptide is 2813 amino acids, with residues 1-22 being the signal peptide, residues 23-763 forming von Willebrand antigen 2, and the remaining 2050 residues (764-2813) constituting vWF. The Uniprot record also provides details of mutations underlying defective vWF activity in the three subtypes of von Willebrand disease.
Species: Human
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| References |
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1. Silence K. (2010)
Single domain VHH antibodies against von Willebrand factor. Patent number: US7807162 B2. Assignee: Ablynx N.V.. Priority date: 20/05/2006. Publication date: 05/10/2010. |
