biperiden   Click here for help

GtoPdb Ligand ID: 7128

Synonyms: Akineton® | biperiden HCl | biperiden lactate
Approved drug
biperiden is an approved drug (FDA (1959))
Compound class: Synthetic organic
Comment: Biperiden is a centrally active anticholinergic drug.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 23.47
Molecular weight 311.22
XLogP 4.1
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OC(C1CC2CC1C=C2)(c1ccccc1)CCN1CCCCC1
Isomeric SMILES OC(C1CC2CC1C=C2)(c1ccccc1)CCN1CCCCC1
InChI InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2
InChI Key YSXKPIUOCJLQIE-UHFFFAOYSA-N
References
1. Bolden C, Cusack B, Richelson E. (1992)
Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells.
J Pharmacol Exp Ther, 260 (2): 576-80. [PMID:1346637]