guanylyl cyclase-activating protein 1

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Ligands
guanylyl cyclase-activating protein 1 (Human, Mouse, Rat)

GtoPdb Ligand ID: 9164

Abbreviated name: GCAP1

Compound class: Endogenous peptide in human, mouse or rat

Comment: GCAP1 is a neuronal calcium sensor that confers Ca²⁺ sensitivity to guanylyl cyclase activity [1].

Species: Human, Mouse, Rat

Summary
Biological activity
References
Structure

References
1. Makino CL, Peshenko IV, Wen XH, Olshevskaya EV, Barrett R, Dizhoor AM. (2008) A role for GCAP2 in regulating the photoresponse. Guanylyl cyclase activation and rod electrophysiology in GUCA1B knock-out mice. J Biol Chem, 283 (43): 29135-43. [PMID:18723510]

References

1. Makino CL, Peshenko IV, Wen XH, Olshevskaya EV, Barrett R, Dizhoor AM. (2008)
A role for GCAP2 in regulating the photoresponse. Guanylyl cyclase activation and rod electrophysiology in GUCA1B knock-out mice.
J Biol Chem, 283 (43): 29135-43. [PMID:18723510]