Synonyms: Krystexxa® | puricase
pegloticase is an approved drug (FDA (2010), EMA (2013))
Compound class:
Peptide or derivative
Comment: Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.
|