pirbuterol   Click here for help

GtoPdb Ligand ID: 7272

Synonyms: CP-24314-1 | CP-24314-14 | CP-2431414 | Maxair®
Approved drug
pirbuterol is an approved drug (FDA (1986))
Compound class: Synthetic organic
Comment: Marketed formulations may contain (PubChem CID 171674).
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Click here for structure editor
Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the CDK toolkit. All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 85.61
Molecular weight 240.15
XLogP 0.37
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES OCc1nc(ccc1O)C(CNC(C)(C)C)O
Isomeric SMILES OCc1nc(ccc1O)C(CNC(C)(C)C)O
InChI InChI=1S/C12H20N2O3/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8/h4-5,11,13,15-17H,6-7H2,1-3H3
InChI Key VQDBNKDJNJQRDG-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1986))
IUPAC Name Click here for help
6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol
International Nonproprietary Names Click here for help
INN number INN
3477 pirbuterol
Synonyms Click here for help
CP-24314-1 | CP-24314-14 | CP-2431414 | Maxair®
Database Links Click here for help
CAS Registry No. 38677-81-5
ChEMBL Ligand CHEMBL1094966
DrugBank Ligand DB01291
DrugCentral Ligand 2199
GtoPdb PubChem SID 178103846
PubChem CID 4845
Search Google for chemical match using the InChIKey VQDBNKDJNJQRDG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VQDBNKDJNJQRDG
Search PubMed clinical trials pirbuterol
Search PubMed titles pirbuterol
Search PubMed titles/abstracts pirbuterol
UniChem Compound Search for chemical match using the InChIKey VQDBNKDJNJQRDG-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey VQDBNKDJNJQRDG-UHFFFAOYSA-N
Wikipedia Pirbuterol