cannabinol   Click here for help

GtoPdb Ligand ID: 740

Compound class: Synthetic organic
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Click here for structure editor
Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the CDK toolkit. All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 29.46
Molecular weight 310.19
XLogP 6.84
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES CCCCCc1cc(O)c2c(c1)OC(c1c2cc(C)cc1)(C)C
Isomeric SMILES CCCCCc1cc(O)c2c(c1)OC(c1c2cc(C)cc1)(C)C
InChI InChI=1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
InChI Key VBGLYOIFKLUMQG-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol
International Nonproprietary Names Click here for help
INN number INN
2887 cannabinol
Database Links Click here for help
Specialist databases
GPCRdb Ligand cannabinol
Other databases
BindingDB Ligand 50061117
CAS Registry No. 521-35-7
ChEBI CHEBI:3360
ChEMBL Ligand CHEMBL74415
GtoPdb PubChem SID 135650052
PubChem CID 2543
Search Google for chemical match using the InChIKey VBGLYOIFKLUMQG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VBGLYOIFKLUMQG
Search PubMed clinical trials cannabinol
Search PubMed titles cannabinol
Search PubMed titles/abstracts cannabinol
UniChem Compound Search for chemical match using the InChIKey VBGLYOIFKLUMQG-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey VBGLYOIFKLUMQG-UHFFFAOYSA-N
Wikipedia Cannabinol

Product suppliers

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Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.

Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.

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Tocris
Cannabinol (links to external site)
Cat. No. 3130