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The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list

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Nucleic acid ligands. Please note, this is a recently added ligand category and its curation is under development.
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A   B   C   D   E   F   G   I   L   M   N   O   P   R   S   T   U   V   Z  

Ligand name ID Synonyms
A Back to top
Apta-1 Immunopharmacology Ligand Antimalarial Ligand 13556
avacincaptad pegol Approved drug Immunopharmacology Ligand 12857 ARC-1905, ARC1905, Izervay®, Zimura
 
B Back to top
bevasiranib 13629
 
C Back to top
casimersen Approved drug 11444 Amondys 45®, SRP-4045, SRP4045
cenersen 8270 Aezea® (proposed proprietary name), EL625
 
D Back to top
danvatirsen 13607 AZD-9150, AZD9150, ISIS STAT3Rx
donidalorsen Approved drug 13610 Dawnzera®, IONIS-PKK-LRx, ISIS 721744, ISIS-721744, ISIS721744
drisapersen 13535 GSK2402968, Kyndrisa®, PRO051
 
E Back to top
edifoligide 13633 CGT-003, CGT003, E2F Duplex Decoy
elsunersen 14130 PRAX-222, PRAX222
eplontersen Approved drug 13606 AKCEA-TTR-LRx, Ionis-TTR-LRx, Wainua®, Wainzua®
 
F Back to top
fesomersen 14081 IONIS-FXI-LRx
fitusiran Approved drug 13630 ALN-57213, ALN-AT3, ALN-AT3SC, Qfitlia®
fomivirsen Approved drug 13533 ISIS 2922, ISIS-2922, ISIS2922, Vitravene®
 
G Back to top
givosiran Approved drug 13614 ALN-AS1, Givlaari®
golodirsen Approved drug 13605 SRP-4053, SRP4053, VYONDYS 53®
 
I Back to top
imetelstat Approved drug 13625 GRN-163, GRN163, Rytelo®
inclisiran Approved drug 13624 ALN-60212, ALN-PCSsc, Leqvio®
inotersen Approved drug 13543 GSK-2998728, GSK2998728, ISIS-420915, ISIS420915, Tegsedi®
 
L Back to top
lepodisiran 13708 LY-3819469, LY3819469
lonvoguran 13712 NTLA-2002, NTLA2002
lumasiran Approved drug 13613 AD-65585, ALN-65585, ALN-G01, Oxlumo®
 
M Back to top
mipomersen Approved drug 7364 ISIS 301012 parent acid, isis-301012, Kynamro®
miravirsen 13534 SPC-3649, SPC3649
mongersen Immunopharmacology Ligand 8277 DNA, d(P-thio)(G-T-m5C-G-C-C-C-C-T-T-C-T-C-C-C-m5C-G-C-A-G-C), GED-0301, GED0301
 
N Back to top
nedosiran Approved drug 13615 DCR-PHXC, NN-7022, Rivfloza®
nusinersen Approved drug 9416 ASO-10-27, BIIB-058, BIIB058, Ionis-SMNrx, ISIS 396443, ISIS SMNRx, ISIS-SMNRx, ISIS396443, Spinraza®
 
O Back to top
oblimersen 8269 DNA, D(P-thio)(T-C-T-C-C-C-A-G-C-G-T-G-C-G-C-C-A-T), G3139, Genasense®
olezarsen Approved drug 13658 AKCEA-APOCIII-LRX, IONIS-APOCIII-LRX, ISIS-678354, ISIS-APOCIII-LRX, Tryngolza®
olpasiran 13709 AMG-890, AMG890
 
P Back to top
patisiran Approved drug 13611 ALN-18328, ALN-TTR02, Onpattro®
pegaptanib Approved drug 6836 EYEOO1, Macugen®, NX183, pegaptanib sodium
pegpleranib 13532 E-01AJ, E-10030, E01AJ, E10030, Fovista®, X-01E, X01E
pelacarsen 13710 TQJ-230, TQJ230
plozasiran 13642 ARO-APOC3
 
R Back to top
remlarsen 13636 MRG-201, MRG201
revusiran 13631 AD-51547, ALN-TTRSC
rondaptivon pegol 13641 BT-200, BT200
 
S Back to top
sapablursen 13914 Ionis-tmprss6-lrx, ISIS 702843, ISIS-702843, ISIS702843
 
T Back to top
tofersen Approved drug 13536 BIIB-067, BIIB067, Qalsody®
 
U Back to top
ulefnersen 13056 ION-363, ION363, Jacifusen
 
V Back to top
viltolarsen Approved drug 11430 NCNP-01, NS-065, Viltepso®
vutrisiran Approved drug 13616 ALN-65492, ALN-TTRSC02, Amvuttra®, votrisiran
 
Z Back to top
zodasiran 13640 ARO-ANG3