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MMP26

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Target not currently curated in GtoImmuPdb

Target id: 1648

Nomenclature: MMP26

Family: M10: Matrix metallopeptidase

Contents:

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 261 11p15.4 MMP26 matrix metallopeptidase 26
Previous and Unofficial Names Click here for help
endometase | matrilysin 2
Database Links Click here for help
Specialist databases
MEROPS M10.029 (Hs)
Other databases
Alphafold Q9NRE1 (Hs)
BRENDA 3.4.24.-
CATH/Gene3D 3.40.390.10
ChEMBL Target CHEMBL4707 (Hs)
DrugBank Target Q9NRE1 (Hs)
Ensembl Gene ENSG00000167346 (Hs)
Entrez Gene 56547 (Hs)
Human Protein Atlas ENSG00000167346 (Hs)
KEGG Enzyme 3.4.24.-
KEGG Gene hsa:56547 (Hs)
OMIM 605470 (Hs)
Pharos Q9NRE1 (Hs)
RefSeq Nucleotide NM_021801 (Hs)
RefSeq Protein NP_068573 (Hs)
UniProtKB Q9NRE1 (Hs)
Wikipedia MMP26 (Hs)
Enzyme Reaction Click here for help
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
ilomastat Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Inhibition 7.8 pIC50 1
⤷ pIC50 7.8 (IC50 1.7x10-8 M) [1]

References

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1. Ma D, Wu W, Yang G, Li J, Li J, Ye Q. (2004) Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett, 14 (1): 47-50. [PMID:14684295]

How to cite this page

M10: Matrix metallopeptidase: MMP26. Last modified on 16/03/2017. Accessed on 29/10/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1648.