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protein kinase AMP-activated non-catalytic subunit beta 2

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Target not currently curated in GtoImmuPdb

Target id: 1544

Nomenclature: protein kinase AMP-activated non-catalytic subunit beta 2

Abbreviated Name: AMPKB2

Family: AMPK subfamily

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 272 1q21.1 PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
Mouse - 36 3 F2.2 Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
Rat - 179 2q34 Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2
Previous and Unofficial Names Click here for help
AMP-activated protein kinase beta-2 regulatory subunit | AMPK subunit beta-2 | protein kinase
Database Links Click here for help
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

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Allosteric Modulators
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
MT47-100 Small molecule or natural product Click here for species-specific activity table Hs Negative 4.6 pKi 1
pKi 4.6 (Ki 2.48x10-5 M) [1]

References

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1. Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE et al.. (2015) Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release. Chem Biol, 22 (6): 705-11. [PMID:26091167]

How to cite this page

AMPK subfamily: protein kinase AMP-activated non-catalytic subunit beta 2. Last modified on 30/03/2016. Accessed on 11/04/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1544.