S10: Carboxypeptidase Y

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

1585

Cathepsin A Show summary »« Hide summary More detailed page go icon to follow link

Serine carboxypeptidase 1 Show summary »« Hide summary

Target Id

1585

Nomenclature

Serine carboxypeptidase 1

Previous and unofficial names

RISC | retinoid inducible serine carboxypeptidase | serine carboxypeptidase 1

Genes

SCPEP1 (Hs), Scpep1 (Mm), Scpep1 (Rn)

Ensembl ID

ENSG00000121064 (Hs), ENSMUSG00000000278 (Mm), ENSRNOG00000002358 (Rn)

UniProtKB AC

Q9HB40 (Hs), Q920A5 (Mm), Q920A6 (Rn)

EC number

3.4.16.-

Vitellogenic carboxypeptidase-like protein Show summary »« Hide summary

Target Id

1583

Nomenclature

Vitellogenic carboxypeptidase-like protein

Previous and unofficial names

Genes

CPVL (Hs), Cpvl (Mm), Cpvl (Rn)

Ensembl ID

ENSG00000106066 (Hs), ENSMUSG00000052955 (Mm), ENSRNOG00000009172 (Rn)

UniProtKB AC

Q9H3G5 (Hs), Q9D3S9 (Mm), Q4QR71 (Rn)

EC number

3.4.16.-

References

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1. Ruf S et al.. (2013) Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases. Patent number: WO2013072327. Assignee: Sanofi. Priority date: 14/11/2011. Publication date: 23/05/2013.

2. Ruf S et al. (2013) Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases. Patent number: WO2013072328. Assignee: Sanofi. Priority date: 14/11/2011. Publication date: 23/05/2013.

3. Ruf S et al. (2014) Biaryl-propionic acid derivatives and their use as pharmaceuticals. Patent number: WO2014154727. Assignee: Sanofi. Priority date: 20/03/2013. Publication date: 02/10/2014.

4. Ruf S, Buning C, Schreuder H, Horstick G, Linz W, Olpp T, Pernerstorfer J, Hiss K, Kroll K, Kannt A et al.. (2012) Novel β-amino acid derivatives as inhibitors of cathepsin A. J Med Chem, 55 (17): 7636-49. [PMID:22861813]

How to cite this family page

Database page citation:

S10: Carboxypeptidase Y. Accessed on 23/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=756.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.