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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 1061 | 19q13.42 | NLRP12 | NLR family pyrin domain containing 12 | |
Mouse | - | 1054 | 7 A1 | Nlrp12 | NLR family, pyrin domain containing 12 | |
Rat | - | - | 1q12 | Nlrp12 | NLR family, pyrin domain containing 12 |
Previous and Unofficial Names ![]() |
CLR19.3 | NALP12 | PAN6 | PYPAF7 | RNO2 | NACHT, leucine rich repeat and PYD containing 12 | Monarch1 | FCAS2 | RNO | NLR family | NLR family, pyrin domain containing 12 |
Database Links ![]() |
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Alphafold | P59046 (Hs), E9Q5R7 (Mm) |
Ensembl Gene | ENSG00000142405 (Hs), ENSMUSG00000078817 (Mm), ENSRNOG00000060745 (Rn) |
Entrez Gene | 91662 (Hs), 378425 (Mm), 292541 (Rn) |
Human Protein Atlas | ENSG00000142405 (Hs) |
KEGG Gene | hsa:91662 (Hs), mmu:378425 (Mm), rno:292541 (Rn) |
OMIM | 609648 (Hs) |
Pharos | P59046 (Hs) |
UniProtKB | P59046 (Hs), E9Q5R7 (Mm) |
Wikipedia | NLRP12 (Hs) |
Immuno Process Associations | ||
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Physiological Functions Comments | |
Involved in inflammasome formation, bacterial control and inflammatory migration. |
Clinically-Relevant Mutations and Pathophysiology ![]() |
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