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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 1043 | 19q13.43 | NLRP13 | NLR family pyrin domain containing 13 |
Previous and Unofficial Names ![]() |
CLR19.7 | NALP13 | NOD14 | PAN13 | NACHT, leucine rich repeat and PYD containing 13 | NLR family, pyrin domain containing 13 |
Database Links ![]() |
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Alphafold | Q86W25 (Hs) |
Ensembl Gene | ENSG00000173572 (Hs) |
Entrez Gene | 126204 (Hs) |
Human Protein Atlas | ENSG00000173572 (Hs) |
KEGG Gene | hsa:126204 (Hs) |
OMIM | 609660 (Hs) |
Pharos | Q86W25 (Hs) |
UniProtKB | Q86W25 (Hs) |
Wikipedia | NLRP13 (Hs) |
Immunopharmacology Comments |
NLRP proteins are critical components of inflammasome complexes and are thereby involved in inflammasome-mediated activation of proinflammatory caspases. NLRP13 has the typical PYD-NACHT-LRR domain structure common to the NLRP protein family [1]. But despite this structural homology the biological function of NLRP13 is not as well defined as other related proteins. |
General Comments |
The function of NLRP13 is not well defined. |