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Target not currently curated in GtoImmuPdb
Target id: 2131
Nomenclature: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Abbreviated Name: Obscn
Family: Trio family
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 7968 | 1q42.13 | OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | |
| Mouse | - | 8886 | 11 B1.3 | Obscn | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | |
| Rat | - | - | 10q22 | Obscn | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | |
| Previous and Unofficial Names |
| Obscurin-MLCK | Obscurin-myosin light chain kinase |
| Database Links |
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| Alphafold | Q5VST9 (Hs), A2AAJ9 (Mm) |
| BRENDA | 2.7.11.1 |
| CATH/Gene3D | 2.30.29.30, 2.60.40.10 |
| Ensembl Gene | ENSG00000154358 (Hs), ENSMUSG00000061462 (Mm), ENSRNOG00000058068 (Rn) |
| Entrez Gene | 84033 (Hs), 380698 (Mm), 338458 (Rn) |
| Human Protein Atlas | ENSG00000154358 (Hs) |
| KEGG Enzyme | 2.7.11.1 |
| KEGG Gene | hsa:84033 (Hs), mmu:380698 (Mm), rno:338458 (Rn) |
| OMIM | 608616 (Hs) |
| Pharos | Q5VST9 (Hs) |
| RefSeq Nucleotide | NM_052843 (Hs), NM_001003914 (Mm) |
| RefSeq Protein | NP_443075 (Hs), NP_001164983 (Mm) |
| UniProtKB | Q5VST9 (Hs), A2AAJ9 (Mm) |
| Wikipedia | OBSCN (Hs) |
| Selected 3D Structures |
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| Enzyme Reaction |
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Trio family: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. Last modified on 01/08/2014. Accessed on 16/01/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2131.
