serine/threonine kinase 31 | Other-unique family | IUPHAR/BPS Guide to PHARMACOLOGY

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serine/threonine kinase 31

Target not currently curated in GtoImmuPdb

Target id: 2220

Nomenclature: serine/threonine kinase 31

Abbreviated Name: STK31

Family: Other-unique family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1019 7 p15.3 STK31 serine/threonine kinase 31
Mouse - 1018 6 B2.3 Stk31 serine threonine kinase 31
Rat - 1018 4q24 Stk31 serine threonine kinase 31
Previous and Unofficial Names
SgK396 | TDRD8
Database Links
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 2.7.11.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 25 [PMID: 17935989] Hs Inhibition <5.8 pKi 1
pKi <5.8 (Ki >1.422x10-6 M) [1]

References

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1. Tao ZF, Chen Z, Bui MH, Kovar P, Johnson E, Bouska J, Zhang H, Rosenberg S, Sowin T, Lin NH. (2007) Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics. Bioorg. Med. Chem. Lett., 17 (23): 6593-601. [PMID:17935989]

How to cite this page

Other-unique family: serine/threonine kinase 31. Last modified on 15/10/2015. Accessed on 08/12/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2220.