trio Rho guanine nucleotide exchange factor | Trio family | IUPHAR/BPS Guide to PHARMACOLOGY

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trio Rho guanine nucleotide exchange factor

Target not currently curated in GtoImmuPdb

Target id: 2255

Nomenclature: trio Rho guanine nucleotide exchange factor

Abbreviated Name: TRIO

Family: Trio family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 3097 5p14-p15.1 TRIO trio Rho guanine nucleotide exchange factor
Mouse - 3103 15 B1 Trio triple functional domain (PTPRF interacting)
Rat - 3104 2q22 Trio trio Rho guanine nucleotide exchange factor
Previous and Unofficial Names
Solo | triple functional domain (PTPRF interacting)
Database Links
BRENDA
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Crystal structure of the first DH/PH domain of Trio to 1.7 A.
PDB Id:  1NTY
Resolution:  1.7Å
Species:  Human
References:  1
Enzyme Reaction
EC Number: 2.7.11.1

References

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1. Skowronek KR, Guo F, Zheng Y, Nassar N. (2004) The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids. J. Biol. Chem., 279 (36): 37895-907. [PMID:15199069]

How to cite this page

Trio family: trio Rho guanine nucleotide exchange factor. Last modified on 18/08/2014. Accessed on 10/07/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2255.