Quaternary Structure: Subunits

GM-CSF receptor, α subunit (Ligand-binding subunit)

Cytokine receptor common β subunit (Other subunit)

Previous and Unofficial Names

GM-CSF receptor

Natural/Endogenous Ligands
G-CSF {Sp: Human}
GM-CSF {Sp: Human}

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Agonists
Key to terms and symbols		Click column headers to sort
Ligand Sp. Action Value Parameter Reference G-CSF {Sp: Human} Hs Agonist - - ⤷ GM-CSF {Sp: Human} Hs Agonist - - ⤷

Immunopharmacology Comments

The functional GM-CSF receptor is a heterodimer consisting of the ligand binding GM-CSF receptor α subunit (CSF2RA) and CSF2RB (cytokine receptor common β subunit). CSF2RB is required for the formation of the functional receptors for IL-3, IL-5 and GM-CSF.