Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	388	6p21.1	PGC	progastricsin
Mouse	-	392	17 23.98 cM	Pgc	progastricsin (pepsinogen C)
Rat	-	392	9q12	Pgc	progastricsin

Previous and Unofficial Names

gastricsin | PG1 | Upg1 | urinary pepsinogen 1 | progastricsin (pepsinogen C)

Database Links
Specialist databases
MEROPS	A01.003 (Hs)
Other databases
Alphafold	P20142 (Hs), Q9D7R7 (Mm), P04073 (Rn)
BRENDA	3.4.23.3
CATH/Gene3D	2.40.70.10
ChEMBL Target	CHEMBL2136 (Hs), CHEMBL2152 (Rn)
Ensembl Gene	ENSG00000096088 (Hs), ENSMUSG00000023987 (Mm), ENSRNOG00000014492 (Rn)
Entrez Gene	5225 (Hs), 109820 (Mm), 24864 (Rn)
Human Protein Atlas	ENSG00000096088 (Hs)
KEGG Enzyme	3.4.23.3
KEGG Gene	hsa:5225 (Hs), mmu:109820 (Mm), rno:24864 (Rn)
OMIM	169740 (Hs)
Pharos	P20142 (Hs)
RefSeq Nucleotide	NM_002630 (Hs), NM_001166424 (Hs), NM_025973 (Mm), NM_133284 (Rn)
RefSeq Protein	NP_001159896 (Hs), NP_002621 (Hs), NP_080249 (Mm), NP_579818 (Rn)
UniProtKB	P20142 (Hs), Q9D7R7 (Mm), P04073 (Rn)
Wikipedia	PGC (Hs)

Enzyme Reaction
EC Number: 3.4.23.3

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 3 [PMID: 8410973] Hs Inhibition 9.1 pKi 1 ⤷ pKi 9.1 (Ki 9x10-10 M) [1]

Immuno Process Associations

Immuno Process:  Immune regulation