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Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 247 | 7q34 | PRSS2 | serine protease 2 | |
| Mouse | - | 246 | 6 B1 | Prss2 | serine protease 2 | |
| Previous and Unofficial Names |
| anionic trypsin-2 | anionic trypsin II | protease | protease, serine, 2 | protease, serine 2 | protease, serine, 2 (trypsin 2) | Tesp4 | Try2 | TRY8 | TRYP | trypsinogen 20 |
| Database Links |
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| Specialist databases | |
| MEROPS | S01.258 (Hs) |
| Other databases | |
| Alphafold | P07478 (Hs), P07146 (Mm) |
| BRENDA | 3.4.21.4 |
| ChEMBL Target | CHEMBL3159 (Hs) |
| Ensembl Gene | ENSG00000275896 (Hs), ENSMUSG00000057163 (Mm) |
| Entrez Gene | 5645 (Hs), 22072 (Mm) |
| Human Protein Atlas | ENSG00000275896 (Hs) |
| KEGG Enzyme | 3.4.21.4 |
| KEGG Gene | hsa:5645 (Hs), mmu:22072 (Mm) |
| OMIM | 601564 (Hs) |
| Orphanet | ORPHA139106 (Hs) |
| Pharos | P07478 (Hs) |
| RefSeq Nucleotide | NM_002770 (Hs), NM_009430 (Mm) |
| RefSeq Protein | NP_002761 (Hs), NP_033456 (Mm) |
| UniProtKB | P07478 (Hs), P07146 (Mm) |
| Wikipedia | PRSS2 (Hs) |
| Enzyme Reaction |
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| Clinically-Relevant Mutations and Pathophysiology
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S1: Chymotrypsin: serine protease 2. Last modified on 27/02/2018. Accessed on 29/10/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2398.
