Ceramide kinase | Enzymes | IUPHAR/BPS Guide to PHARMACOLOGY

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Ceramide turnover
Ceramide kinase

Ceramide kinase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

2473

ceramide kinase C Show summary »« Hide summary

Target Id

2473

Nomenclature

ceramide kinase

Previous and unofficial names

Lipid kinase 4 | LK4 | Acylsphingosine kinase

Genes

CERK (Hs), Cerk (Mm), Cerk (Rn)

Ensembl ID

ENSG00000100422 (Hs), ENSMUSG00000035891 (Mm), ENSRNOG00000017022 (Rn)

UniProtKB AC

Q8TCT0 (Hs), Q8K4Q7 (Mm)

EC number

2.7.1.138

ceramide + ATP -> ceramide 1-phosphate + ADP

Inhibitors

NVP 231 pIC₅₀ 7.9 [1]

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.