Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	237	12p13.31	CLEC4A	C-type lectin domain family 4 member A	1
Mouse	1	238	6 58.18 cM	Clec4a2	C-type lectin domain family 4, member a2
Rat	1	237	4q42	Clec4a3	C-type lectin domain family 4, member A3
Gene and Protein Information Comments
Variants encoding shorter isoforms of human DCIR are reported. Two splice variants of the mouse gene encode identical shorter protein isoforms, compared to isoform 1 presented here..

Previous and Unofficial Names

CD367 | CLECSF6 | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 | Dendritic cell (DC) immunoreceptor (IR) | C-type lectin domain family 4, member A3 | C-type lectin domain family 4, member a2 | C-type lectin domain family 4

Database Links
Alphafold	Q9UMR7 (Hs), Q9QZ15 (Mm)
CATH/Gene3D	3.10.100.10
Ensembl Gene	ENSG00000111729 (Hs), ENSMUSG00000030148 (Mm), ENSRNOG00000010018 (Rn)
Entrez Gene	50856 (Hs), 26888 (Mm), 362431 (Rn)
Human Protein Atlas	ENSG00000111729 (Hs)
KEGG Gene	hsa:50856 (Hs), mmu:26888 (Mm), rno:362431 (Rn)
OMIM	605306 (Hs)
Pharos	Q9UMR7 (Hs)
RefSeq Nucleotide	NM_016184 (Hs), NM_001170333 (Mm), NM_001005891 (Rn)
RefSeq Protein	NP_057268 (Hs), NP_001163804 (Mm), NP_001005891 (Rn)
UniProtKB	Q9UMR7 (Hs), Q9QZ15 (Mm)
Wikipedia	CLEC4A (Hs)

Immunopharmacology Comments

CLEC4A is an pattern recognition receptor and immunoreceptor that functions in cell adhesion, cell-cell signalling, glycoprotein turnover, and plays roles in inflammation and the immune response. It contains a immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain.

Cell Type Associations

Immuno Cell Type:  Dendritic cells Cell Ontology Term:   dendritic cell (CL:0000451) References:  1