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Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| SARS-CoV-2 | - | 61 | Orf6 | Non-structural protein 6 | ||
| SARS-CoV | - | 63 | Orf6 | Non-structural protein 6 | ||
| Previous and Unofficial Names |
| nsp6 |
| Database Links |
|
| Entrez Gene | 43740578 (SARS-CoV-2), 1489673 (SARS-CoV) |
| RefSeq Protein | YP_009825056 (SARS-CoV), YP_009725302 (SARS-CoV-2) |
| UniProtKB | P0DTC6 (SARS-CoV-2), P59634 (SARS-CoV) |
| General Comments |
| Coronavirus nsp6 proteins limit autophagosome expansion [1]. This mechanism may favour coronavirus infection by damaging autophagosome-mediated delivery of viral components to lysosomes for degradation. |
