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Natural cytotoxicity triggering receptor 3 (CD337)

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 3141

Nomenclature: Natural cytotoxicity triggering receptor 3 (CD337)

Abbreviated Name: NKp30

Family: CD molecules

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 201 6p21.33 NCR3 natural cytotoxicity triggering receptor 3
Mouse - - 17 B1 Ncr3-ps natural cytotoxicity triggering receptor 3, pseudogene
Rat 1 192 20p12 Ncr3 natural cytotoxicity triggering receptor 3
Previous and Unofficial Names Click here for help
natural cytotoxicity triggering receptor 3, pseudogene | natural cytotoxicity triggering receptor 3
Database Links Click here for help
Alphafold
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
Pharos
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file go icon to follow link

Activators
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Value Parameter Reference
Natural cytotoxicity triggering receptor 3 ligand 1 {Sp: Human} Peptide Immunopharmacology Ligand Hs Activation - -
Large proline-rich protein BAG6 Peptide Immunopharmacology Ligand Hs Activation - -
Immunopharmacology Comments
Activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands.

How to cite this page

CD molecules: Natural cytotoxicity triggering receptor 3 (CD337). Last modified on 30/07/2020. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=3141.