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Target not currently curated in GtoImmuPdb
Target id: 3177
Nomenclature: FKBP prolyl isomerase 8
Abbreviated Name: FKBP38
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 413 | 19p13.11 | FKBP8 | FKBP prolyl isomerase 8 | |
Mouse | - | 403 | Ch 8, 34.15 cM, cytoband C1 | Fkbp8 | FK506 binding protein 8 | |
Rat | - | 403 | 16p14 | Fkbp8 | FKBP prolyl isomerase 8 |
Previous and Unofficial Names |
K506 binding protein 8 | FKBP38 | FKBPr38 | K506-binding protein 8 (38kD) |
Database Links | |
Alphafold | Q14318 (Hs), O35465 (Mm), Q3B7U9 (Rn) |
BRENDA | 5.2.1.8 |
Ensembl Gene | ENSG00000105701 (Hs), ENSMUSG00000019428 (Mm), ENSRNOG00000058359 (Rn) |
Entrez Gene | 23770 (Hs), 14232 (Mm), 290652 (Rn) |
Human Protein Atlas | ENSG00000105701 (Hs) |
KEGG Enzyme | 5.2.1.8 |
KEGG Gene | hsa:23770 (Hs), mmu:14232 (Mm), rno:290652 (Rn) |
OMIM | 604840 (Hs) |
Pharos | Q14318 (Hs) |
RefSeq Nucleotide | NM_012181 (Hs), NM_001111066 (Mm), NM_001037180 (Rn) |
RefSeq Protein | NP_036313 (Hs), NP_001104536 (Mm), NP_001032257 (Rn) |
UniProtKB | Q14318 (Hs), O35465 (Mm), Q3B7U9 (Rn) |
Wikipedia | FKBP8 (Hs) |
Enzyme Reaction | ||||
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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1. Edlich F, Weiwad M, Wildemann D, Jarczowski F, Kilka S, Moutty MC, Jahreis G, Lücke C, Schmidt W, Striggow F et al.. (2006) The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia. J Biol Chem, 281 (21): 14961-70. [PMID:16547004]